20:08
societynews[dot] org
A cheap, highly portable blood test has published a study Sunday so just like expensive hospital-based analysis for the detection of HIV, syphilis and other infectious diseases, proved its worth.
Researchers tested prototypes of the credit card size lab-on-a-chip with hundreds of patients in Rwanda, reporting almost 100 percent accuracy.
The so called "mChip", said could help translate three obstacles to the effective delivery of health care in the poorest regions of the world: difficult access, high costs and long delays for results.
"The idea is, a large class of diagnostic tests in each setting in the world, rather than they force to go, to a clinic to draw blood and then wait to make patient days for their results," said Samuel SIA, a professor at Columbia University and lead developer.
The results were published in Nature Medicine.
With projected production costs of one dollar per unit, it would be mChip far cheaper to administer than current lab-based testing.
Because in several proteins can scan each correspond to a disease, with a single blood sample at the same time it is probably still billiger-and genauer--strips as the work such as pregnancy testsstore-bought.
"Current HIV rapid tests require subjective interpretation of the band intensity by the user, which may lead to false positives", noticed that is healthy individuals is incorrectly diagnosed the study.
The mChip can be in contrast to measure with a hundred-dollar handheld instrument not more complicated to use than a mobile phone, according to the researchers.
Finally, the device delivers results in minutes rather than days or weeks, a time-saving can be a big difference in outcomes.
The device contains a microchip within an injection molded plastic housing located, explains Vincent Chief technological officer at Claros Diagnostics, owns or has licensed relevant patents Linder.
Bind unique disease "Biomarkers" in a pin down blood sample contained to one of up to 10 individual zones.
A nano-scale gold "Reagent" - which is a substance by a chemical reaction - is injected followed by a silver one with gold, an ultra-thin film produce interacts.
"The darkness of the film is proportional to the concentration of biomarkers in the sample", said the steps to the process of development in non-digital photography compare Linder.
With a LED-based detector measured are, or can be evaluated by the naked eye.
In Rwanda SIA and colleagues tested the device in the Muhima hospital in Kigali, where local results take at present days or weeks as samples to an external laboratory must be sent.
Half and half, only tested by a total of 70 copies with known HIV status false, a result, the accuracy of HIV test environment analysis rivals.
Similar tests on more than 100 archived copies equally reliable results gezeitigt such as further studies based on samples of female sex workers are known to be infected with HIV and syphilis.
The researchers hope that it will boost testing of pregnant women, particularly in Africa.
Currently just under a quarter of pregnant women in low and middle income countries are tested for HIV, a number, which offers little hope by 2015 to reach the UN target of elimination of mother-to child transmission according to the 2010 UNAIDS report on the global AIDS epidemic.
You get HIV tests, according to the report present in Zambia and the Democratic Republic of the Congo, for example, only nine and six percent, or pregnant women.
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